McGarrett sets up a cordon of police around a young woman to capture her boyfriend who has escaped from jail, but all is not as it seems…
When Pete runs into an old girlfriend, she invites him to her birthday party but he turns her down, only to be kidnapped by her two friends and forced to attend the party.
A band of ex-Confederate soldiers demands $25,000 from Ben. When Hoss resists their demands and tries to fight them, their leader, Shanklin, shoots Hoss in the abdomen. Hoss lingers near death, and when the doctor is unable to complete the surgery, a nearly inconsolable Ben persuades Shanklin (a confident, competent doctor) to save his son's life. Meanwhile, Jamie - who had witnessed the shooting and nearly got shot himself - searches high and low for Joe, who is involved with a beautiful starlet and intently focused on a poker match.
"I know that Tabitha is ready for school, but is school ready for Tabitha?" warns Sam. Tabitha attends school for the first time, and has a pretty hard time because a boy is messing with her. When he refuses to give up, Tabitha turns him into a frog. The teacher Miss Peabody gets on her about the frog and tells her to put it back in the class terrarium. Tabitha grabs the wrong frog and Samantha pops into the school and changes the frogs. When the right frog is brought home, Tabitha changes it back before the boy's mother finds out.
Shanks and Blake are Syndicate men who run the loan shark racket in the Islands and are preparing to transfer $10 million to the mainland, leading to the Syndicate expanding their operations there. The IMF must stop the Syndicate's expansion. In Hawaii the IMF's in-and-out operation goes bad when Willy is captured and turned over to Dr. Matier, who injects him with a near-lethal truth serum. To get Willy out and finish the mission, Casey approaches Shanks and drugs him into helping the IMF steal the $10 million, while Jim approaches Blake and claims to be a Syndicate man from the mainland. The IMF make Shanks ""disappear,"" presumed dead, to convince Blake his partner sold him out. Then Casey wakes up Shanks and Jim and Blake confront him - Casey's fake ""confession"" seals the deal but then Syndicate man Barney fake-shoots Jim and Casey just as Syndicate man Bolt arrives. Confused, Bolt takes them all to Willy hoping his information will straighten things out. Willy manages to escape wit
The Doctor is sentenced to fight Grun to the death and his attempt to escape leads to an encounter with Aggedor.
The crew of Los Angeles County Fire Department Station 51, particularly the paramedic team, and Rampart Hospital respond to emergencies in their operating area.
When Rhoda's apartment is destroyed by fire, she moves in with Mary. The two find that while they are best friends, they make awful roommates.
Archie is too proud to let Edith accept a mink stolen from her cousin Amelia, until he sees a chance to make a three-hundred-dollar profit.
Lamont comes down hard on Fred to try to get him to quit smoking and has him go to the doctor for a chest x-ray. Later, the results are sent in the mail and Fred becomes convinced he has tuberculosis.
Felix overreacts when his daughter dates a reform school inmate.
It's a battle of the sexes as Shirley and Laurie prove to their male chauvinist counterparts to be better able to handle the wilderness.
To retain the family jewels, an elderly Russian duchess must present proof of her marriage into the Russian Royal Family, which she says she can do with the help of a journal kept by one of Brett's uncles.
Hannibal Heyes and Kid Curry, two of the most wanted outlaws in the history of the West, are popular "with everyone except the railroads and the banks".
A ghastly shocker about a surgery instructor unconcerned about the source of his cadavers. Convinced that her husband is trying to worry her to death, a distraught housewife files a complaint with the police. A gangster on the lam engages the services of a compliant exporter.
An architect kills his business partner and deliberately lets Columbo suspect him, leading Columbo to think that he's hidden the body in the foundation of a building under construction. He plans to let Columbo dig up the site and find nothing, knowing that its the perfect place to hide the body since Columbo would never look in the same place twice.
Three real estate crooks die horrible and mysterious shellfish related deaths, and McGarrett and the others must establish the link between them, and who has reason to want them dead.