Howard and Joanne Sharp are going to have a baby. Like many people in the near future, they are mulling over the possibility of black-market genetic enhancement. The upside is a perfect baby, able to compete with all those other perfect babies created by the popular, but illegal process. The downside is GRS - Genetic Rejection Syndrome - which turns one in every 10,000 genetically enhanced babies into a monster. The Sharps are willing to take the risk and go ahead with the procedure. Then they learn of the dark secret that their neighbors and best friends, Tony and Fran Blake, keep in the basement.
Gee is sent upstairs to see Barnfather and everyone speculates about the vacant Captain's position. Lewis and Kellerman are sent to Pennsylvania to extradite a woman back to Baltimore where she is a suspect in the murder of her husband. Munch tries to find a videotape in Brodie's pile. Later after reviewing the tape, they discover a key piece of evidence isn't contained on the tape. Munch wants the tape erased, but Brodie delivers the tape to court and that results in the outcome Munch feared. On the trip back from Harrisburg, Kellerman convinces Lewis that they have time to stop at Neptune's Castle and they lose the suspect, for a moment. Later they lose her again but find her at the house of her dead husband's mistress, delivering a hat. Much to everyone's surprise but not the viewers Gaffney is promoted to Captain over Gee. Captain Gaffney lays down the law.
Mark becomes a student guidance counselor and advises an egotistical football player.
Probability is a way to measure how likely it is that something will happen. Probabilities are predictions. They’re often just very careful guesses. When a scientist wants to calculate a probability, she or he gathers data and then uses the data to make her or his guess. Probabilities are between 100% (it’s definitely going to happen) and 0% (forget about it, pal, it’s not going to happen). Most things have a probability somewhere in between.
Steve heads up the investigation when a serial cop killer is on the prowl, while inadvertantly dating the killer.
Monica caters the wedding of Ross's ex-wife and her lesbian lover. Phoebe is possessed by the spirit of an 82-year-old massage client who dies in the middle of a session. And Rachel's mom comes to visit and drops a bombshell.
Williams and Torres investigate the murder of a free-lance writer. Moreno gets a visit by her missing husband.
Lucas may have corrupted the local priest, Father Tilden, and he may be able to take his revenge on townspeople who cross his path. But not even he can control the seemingly miraculous activities of the dead Merlyn, determined to make Lucas answer for his crimes.
A teenage boy finds himself recruited as a member of an elite team of pilots by his father.
A life-altering experience reawakens Drew's aspiration to spend his life behind an altar--as a minister. But his renewed devotion leads to a baptism of fire when he's called upon to dispense advice.
After a woman mistakes Sarah for someone else's daughter, she decides to try to find her birth mother. They find her on the list and Bailey calls her behind Sarah's back. He meets her. She's an actress and she tells him that she doesn't want to meet her. Bailey tells Sarah that the woman in the list is not her mother, killing her hopes. Charlie tries to teach Owen how to poop in the potter so he can go to pre-school. Claudia is shocked when she finds out that Kristen is dating a guy. She tries to make Kristen come back to the family, but Kristen tells her that she has to move on. Justin's friend Allison comes from England to visit him. At first, Julia is jealous, but then they really get along. Allison comes on to Julia, who later reveals her secret. Julia advises Allison not to run away from her problems.
The death of a show horse leads to a trial involving insurance fraud, a sting operation and a wealthy woman's disappearance.
Kelly reunites with Colin and spends all her time getting high. The couple becomes consumed by its habit, especially when supplies run low. Valerie realizes that Kelly is using drugs, but has difficulty convincing everyone else. During a jog, Susan breaks down in tears after she and Brandon pass the scene of a hit-and-run. She reveals that her older sister was struck by a car and killed while jogging with Susan. Donna's concern for Joe's health grows when he intensifies his training sessions. Brandon has a talk with Joe, and is angry when Susan wants to run a story about his condition. Susan fears that Joe's life could be in danger, while Brandon doesn't want rumors to affect Joe's chances at a pro career. Joe nearly collapses with an irregular heartbeat while running the stadium steps. Clare challenges Steve to a race after he belittles her new sports car. A cop pulls them over, and they must attend traffic school. A fellow student, impressed by their bickering, asks Steve and Clare t
Brad feels jealous when Randy starts taking advanced classes at his school. Tim designs the man's bedroom.
It's Roy's 12th birthday (he was born on a leap year), and Helen contacts Roy's son R.J. and convinces him to come back to Nantucket for the party. But the initial reconciliation is dashed when R.J. brings his significant other to the party. Meanwhile, Brian helps Antonio out by driving the cab while Antonio waits for his driver's license.
When Tommy catches a bug, the crew gets its first taste of human illness.
Two dimwitted teenagers discuss TV, heavy-metal music, nachos, and trying to "score with chicks." When the duo aren't sitting on the couch, they try to pick up girls at the local convenience store, slack off at school, or wreak havoc while working at a burger joint.
Frasier befriends Bob, a wheelchair-bound man whom he doesn't have the heart to "dump" after he discovers they have nothing in common.
Roseanne advises an unhappy Becky to change her life -- not realizing that Mark doesn't share his wife's eagerness for change, so Becky intends to change her marriage.
A basketball game, held in the memory of a young boy, erupts into violence. 2 dead, 7 wounded. Andy has a race relation's problem with the organizer of the event that was witnessed by a reporter. Fancy and Sipowicz's relationship is on shaky ground as details of this event come to light and Andy is removed from the case.