The candidates are now two teams of five women and five men, competing on diagnosing and treating a wheelchair-bound man. Meanwhile House does experiments on himself to test what happens after death, and Foreman, at another hospital, is treating his team in a House-like manner.
Is life full of turning points or breaking points? Suddenly everyone in the Sutton household has to decide. For Eddie, it's deciding whether to stay on the streets or become a precint insider by applying for sergeant. For Jenn, it's balancing her love of her work with the dangers of the clinic. And for Cassie, it's having the guts to pursue her painting despite what the critics might say. But this proves easier said than done. With Charles MIA, Cassie feels like she's in free fall. She can hardly get out of bed. But that's only until her Prince Charming appears at the door, waiting to escort her to her very first gallery show as a real painter. Has Charles come back, or is Luc rushing in to take his place? Which one can Cassie really trust?
Denny believes a bet against Carl Sack in a cockfighting case is a sure thing; Alan and Lorraine represent an HIV-positive girl in a suit against her school; a widow hires Katie and Jerry after her husband commits suicide.
George and The Man run into Steve at the local movie theater taking down signs for the old movies, which the manager lets him have. Steve tells George that he collects all of the posters which makes George want a collection of his own of sorts. When he sees a guy taking down a sign, he decides to collect various signs from around the city. So he goes around the city taking every sign from the park, zoo, and science museum. When he goes back out to look for more, he notices the park in chaos. Realizing that it is because the signs are gone, he decides to put them back. George puts back all of the signs but does not put them in their original places causing more chaos. The Man then tells George that each sign has a meaning and they are not just for decoration.
George is pretty mad at Hundley who will simply not let him play in the lobby and wishes Hundley could be more like him. One day though, he notices that Hundley is barking loudly and acting bouncy and playful, much to his wish! He then notices that Hundley seems to go back and forth between acting bouncy and playful, and acting like his normal self. Realizing that something is not normal about Hundley's split personality, he tries to figure out what is going on.
The house romance takes a turn that could ruin one of the teams. Meanwhile, as voted by viewers, the geeks are challenged to massage the ladies while the beauties are challenged with rocket science.
Lt. Colonel Mann joins Gibbs in an investigation of the murder of a Marine Captain who had access to highly classified information. Things get very personal for Gibbs when one of the witnesses in the case turns out to be one of his ex-wives.
When career criminal Wolfgang West gets put away for four years, his wife Cheryl decides it's time for her family to go straight. But can the Wests change the habits of a lifetime?
Things get kinky when Booth and Brennan follow murder clues that lead to a lodge used as an S&M retreat for "jockeys" and their "horses." Meanwhile, Angela tries hypnosis in an effort to figure out her elusive husband's name so she can finally divorce him.
A teacher claims that a student pursued her after she's charged with raping him.
Henry is stuck in Madame Tutu's ballet class when he'd rather go to Karate.
Sam, Ben, and Sock must hunt an escaped soul that uses insects to kill the people living at an apartment complex. Also, Sam is crushed when Andi meets a new guy who encourages her to go back to school full-time and quit her job.
Patty offers Ellen her job back, however, Ellen declines but volunteers to keep helping Patty with the Frobisher case. Lila is back, and bringing more havoc into David and Ellen's lives. Patty uses the newly acquired evidence to blackmail Ray, and offers him an ultimatum.
Five teenagers must locate and secure ancient relics with unbelievable power, while at the same time stop a demonic corporation who want the relics for their power.
Hank's comments on Karen's eating habits prompt her to join a spin class at the local gym, and she's shocked to find out who the teacher is. Lacey gets involved in a "Ladies of Dog River" charity calendar, but is shocked to find out just what she has to do to be "Miss April". Wanda buys a new phone for Corner Gas, but won't let anyone use it until it's fully charged, but then it goes missing.
After the funeral of Hank's father Al, Hank comes back to L.A. with a new manuscript, that he wants Karen to read. After receiving a bonus paycheck, he buys a new car for himself and a new guitar for Becca.
George is at Betsy's birthday party and sees that they have something he has never seen before, a piñata! After George is told how to play, he goes on a free-swinging spree and winds up breaking everything in the backyard BUT the piñata! Aunt Margret tells George to stay outside and play with Charkie and asks him to put his blindfold on and follow her around the backyard with his other senses. Charkie soon escapes the backyard and a blind George begins to follow her around the city in a way other than seeing her.
The Man With the Yellow Hat is about to get a big job! He is going to go up into space to fix the Einstein-Pizza Space Telescope, which is broken and pointed right at Pizza's kitchen window. Dr. Einstein and Professor Pizza explain that the spaceship has a self-locking air lock but they accidentally forgot to make a way to open it from outside. George has to tag along to push the button that would let him in but is forced to go outside and do the job when the Man's tether breaks. Worse off, George is told he has only 2 minutes of air to complete the job.